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Our laboratory primarily uses genomic and biochemical approaches to investigate molecular mechanisms of prostate cancer development and progression. Our current research focuses on androgen receptor (AR)-regulated gene expression and how AR signaling cross talks with other signaling pathways in prostate cancer, such as WNT signaling and DNA repair pathway. The goal of our research is to understand how these genes and pathways function under androgen-deprived conditions and develop novel treatments for incurable castration-resistant prostate cancer.

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